Skip to content

A City-wide DC Cohort of HIV Infected Persons in Care in the District of Columbia
Goal:
The overall purpose of this study is to establish a clinic-based city-wide longitudinal cohort that will describe clinical outcomes in outpatients with HIV/AIDS receiving care in Washington, DC, to improve HIV/AIDS care in DC.
Funder:
National Institute on Drug Abuse
Site Principal Investigator:
Michael Horberg

Center for Effectiveness & Safety Research (CESR)
Goal:
Develop, standardize and improve research infrastructure for inter-regional research studies and perform rapid turnaround research that addresses questions of interest to Kaiser Permanente and the nation.
Funder: KP Operational Funds (National)
Site Principal Investigator: Michael Horberg

Cohort Study of Patients with Disorders of Sex Development (DSD)
Goal:
The goal of this proposal is to compare DSD (Disorders of Sex Development) Quality of Care Indicators (QCI) against actual DSD management delivered at large nationwide integrated HCSs. We will estimate the percentage of DSD patients who received care according to each QCI, compare incidence and prevalence of co-morbidities in DSD patients to the corresponding measures among frequency-matched patients, and assess the proportion of prophylactic gonadectomies that show malignant or precursor lesions on the resulting pathology specimens.
Funder:
 NICHD 
Site Primary Investigator
: Suma Vupputuri

COMpAAAS Tripartite: ART-CC, KP, and VA
Goal:
The purpose of the overall study is to participate in a scientific collaboration across three grant partners to assemble data sets, including electronic health record data. Partners will interpret and disseminate the results of the study through conference abstracts and manuscripts.
Funder:
National Institute of Health
Principal Investigator:
Michael Horberg

Database cohort study to assess the risk of serious angioedema in association with LCZ696 (sacubitril/valsartan; Entresto) use in Black patients with heart failure in the United States.
Goal:
This study will provide estimates of the incidence of angioedema among HF patients initiating sacubitril/valsartan and HF patients initiating an angiotensin-converting enzyme inhibitor (ACEI), with a primary focus on Black HF patients. These estimates will quantify the risk of angioedema among HF patients initiating sacubitril/valsartan compared to HF patients initiating an ACEI.
Investigator:
Douglas Roblin

Development of Chronic Kidney Disease (CKD) and End-Stage Renal Disease Registry
Goal:
The objective of this project is to support internal, inter-regional, and external research related to CKD and ESRD.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator:
Eric Watson

Development of Virtual Data Warehouse (VDW) and Research Data Warehouse (RDW)
Goal:
The goal of this project is to provide a common set of data elements and structures to increase the efficiency of developing and running scripts across different sites, allowing for more seamless research across multiple sites. The goal of the RDW is to create an integrated view from the multiple systems that house the data that constitute the Kaiser Permanente Electronic Health Records.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator:
Eric Watson

Feasibility and Assessment of a Cascade Traceback Screening (FACTS) Program  
Funder: National Cancer Institute
Principal Investigator: Cabell Jonas, PhD, Alanna Rahm, PhD, Nora Henrikson, PhD

Gastric Cancer Surgical Outcomes
Goal:
This collaborative pilot project with Johns Hopkins University aims to compare predictive comorbidity indexes for surgical outcomes of patients with gastric cancer, including overall survival and readmission rates.
Funder:
Kaiser Permanente Community Benefit Program
Principal Investigator:
Monica Ter-Minassian

HIV Infection, Use of Tenofovir and Other Antiretrovirals, and Risk of Fatal and Non-Fatal Comorbidities: Cohort Study in Kaiser Permanente
Goal:
The purpose of the overall study is to primarily compare the incidence rate of fatal and non-fatal comorbidities in HIV patients with incidence rates among matched HIV-uninfected controls, and HIV-uninfected individuals prescribed PrEP.
Funder:
Gilead, Inc.
Multiple Principal Investigator:
Michael Horberg

HIV Status and Incidence and Outcomes of Heart Failure
Goal:
The overall purpose of this study is to work with our clinical and policy leaders in HIV and CHF care to quantify the risk of congestive heart failure (CHF) among HIV-infected patients, which antiretroviral therapy medications have increased risk for CHF and which may be protective, as well as develop care patterns for CHF among our HIV-infected patients.
Funder:
National Heart, Lung, and Blood Institute
Co-Investigator:
Micheal Horberg

Implementing Computerized Substance Use and Depression Screening and Evidence-Based Treatments in an HIV Primary Care Population
Goal:
The purpose of the overall study is to address the important topic of alcohol, smoking, and other substance use and comorbidity screening and treatment among HIV-impacted patients. This study represents an important next step in the evolution of our top-quality HIV care in the context of an aging HIV patient population and has important implications beyond the Kaiser Permanente system.
Funder:
National Institute on Alcohol, Abuse, and Alcoholism
Principal Investigator:
Michael Horberg

Interregional Utilization of Low-Value Interventions for Cancer Care
Goal:
The goals of this project are to assess the feasibility of measuring adherence with the five American Board of Internal Medicine/American Society of Clinical Oncology “Choosing Wisely” practices for low-value cancer care, and to measure adherence and the system-level factors associated with adherence to these measures within three Kaiser Permanente regions.
Funder: CESR
Site Principal Investigator: Douglas Roblin

Kaiser Permanente HIV Quality Improvement and Performance Program
Goal:
We seek to determine quantitative measures of HIV care and outcomes in Kaiser Permanente. We seek to initiate quality improvement programs where we determine there are opportunities for improvement.
Funder
: Care Management Institute/The Permanente Federation/Kaiser Health Plans
Project and Overall Clinical Leader: Michael Horberg

Kaiser Permanente Research Bank
Goal:
The Kaiser Permanente (KP) Research Bank is a nationwide research bank that facilitates studies related to the prevention, diagnosis, and treatment of disease.
Funder: Kaiser Permanente Community Benefit, National Program Office
Site Principal Investigator: Michael Horberg

KPMA Hepatitis Registries
Goal:
The development of the hepatitis B and C registries is critical to ongoing research efforts for KPMA. The hepatitis C registry case finding and registry population is ongoing, with the development of hepatitis B and cirrhosis registries next. Both epidemiologic and clinical applications are anticipated.
Funder: Kaiser Permanente Mid-Atlantic Community Benefits
Principal Investigator (MAPRI):
Michael Horberg

KPMA HIV Registry
Goal:
Develop an HIV registry that closely aligns with the other KP regions’ case definitions. This registry will be used to identify populations for potential research studies, clinical trials, and clinical applications as required.
Funder:
Kaiser Permanente Mid-Atlantic Community Benefits
Principal Investigator:
Michael Horberg

KPMA Sickle Cell Disease Registry
Goal: Develop a sickle cell disease registry that closely aligns with the other KP regions’ case definitions. The registry will be used to facilitate future IRB-approved research based on known cases within the registry, improve care, and enhance clinical decision-making.
Funder: Kaiser Permanente Mid-Atlantic Community Benefits
Principal Investigator (MAPRI):
Michael Horberg

North American AIDS Cohorts Collaboration on Research and Design (NA-ACCORD)
Goal:
This is the North American response to IeDEA, in which Kaiser Permanente Northern California participates. It is a collaborative cohort compendium and analysis for the purpose of achieving sufficient power to address issues that could not be adequately addressed by single cohorts.
Funder:
National Institute of Allergy and Infectious Diseases
Site Principal Investigator
: Michael Horberg

Oncology Epidemiology
Goal:
The goal of this project is to work with the KPMAS cancer registry to monitor cancer incidence, treatment, and survival of all patients diagnosed with cancer at Kaiser Permanente Mid-Atlantic States.
Funder:  Kaiser Permanente Mid-Atlantic Community Benefits
Site Principal Investigator
: Monica Ter-Minassian

Sentinel Data Partner Infrastructure and Querying
Goal:
Contract to provide drug safety surveillance data for the multisite Federal Drug Administration Sentinel project.
Funder:
FDA HHSF223201400030I
Principal Investigator:
Monica Ter-Minassian

Sickle Cell Disease Registry
Goal: 
The goal of this project is to monitor Sickle Cell Disease incidence, treatment, and vaccinations of patients diagnosed at Kaiser Permanente Mid-Atlantic States.
Funder:  Kaiser Permanente Community Benefit Program
Principal Investigator:
Monica Ter-Minassian

The Effect of Health Information Exchange on the Duplication of Radiological Services
Goal:
Determine if comprehensive health information exchange through the electronic health record reduces the rate of follow-up X-rays for simple bone fractures.
Funder: KPMAS Community Benefit
Principal Investigator: Douglas Roblin

Virtual Tumor Registry
Goal:
The goal of this project is to create resources for future internal research projects, as well as inter-regional and extramural research collaborations.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Michael Horberg

Back To Top